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There is a tendency to see increased levels of muscle aches in individuals taking statins, but the exact rate is difficult to determine and is probably in the 5 to 6% range, slightly higher than the aches seen in the patients on the placebo. There has been a recent study that looked at diabetic patients with elevated triglycerides and reduced HDL, finally. When these agents are used as the sole therapy of elevated cholesterol, they have had limited and inconsistent success in reducing myocardial infarction and other events like fatal myocardial infarction or the overall death rate. As well as ignoring the early deaths and crippling heart disease that occurred as a result of untreated high cholesterol, this campaign especially ignored the terrific risk of not treating cholesterol in high-risk patients. Also, following the onset of the national campaign to treat and control hypertension that started in the 1967s, we have seen a dramatic decline in the rate of death from heart disease.
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